Profile Detail

Michel Modo, PhD

Associate Professor
E-Mail:

Interest (in 3 to 10 words):

Medical / Graduate School 1997-1998 MSc Neuroscience, Institute of Psychiatry, King's College London
1998-2001 PhD Neuroscience, Institute of Psychiatry, King's College London
Residency
Clinical / Post-doctoral Fellowship 2001-2005 Post-doctoral Fellow, Institute of Psychiatry, King's College London
Specialties
& Programs
MR
Pre-clinical
Translational
Clinical Interest
Research Interest Cellular MRI, Stroke, Translational Medicine, Neural Stem Cells, Cell Transplantation, Biomaterials, MRI contrast agents, Tissue Engineering
Selected Publications   Modo, M., Hitchens, K., Liu, J., Richardson, R.M. Ex vivo mesoscale diffusion MRI reveals an aberrant collateral mossy fiber connection between dentate gyrus and the stratum moleculare layer in a patient with uncontrolled temporal lobe epilepsy. Human Brain Mapping. 2016; 37(2):780-795. PMID: 26611565.

Nicholls, F., Rotz, M.W., Ling, W., Ghuman, H., MacRenaris, K.W., Meade, T.J., Modo, M. DNA-Gadolinium-Gold nanoparticles for in vivo T1 MR imaging of transplanted human neural stem cells. Biomaterials. 2016; 77: 291-306. PMID: 26615367.

Nicholls, F., Ling, W., Ferrauto, G., Aime, S., Modo, M. Simultaneous MR imaging for tissue engineering in a rat model of stroke. Scientific Reports. 2015; 5: 14597. PMID: 26419200.

Massensini, A., Ghuman, H., Medberry, C.J., Ling, W., Nicholls, F.J., Badylak, S.F., Modo, M. Concentration-dependent intracerebral delivery of ECM hydrogel to a stroke cavity. Acta Biomaterialia. 2015; 27:116-130. PMID: 26318805.

Naumova, A.V., Modo, M., Moore, A., Murry, C.E., Frank, J.A. Clinical imaging in regenerative medicine. Nature Biotechnology. 2014; 32(8): 804-818. PMID: 25093889.

Vernon, A.C., Crum, W.R., Lerch, J.P., Chege, W., Natesan, S., Modo, M., Cooper, J.D., Williams, S.C.R., Kapur, S. Reduced cortical volume and elevated astrocyte density in rats chronically treated with antipsychotic drugs linking MRI findings to cellular pathology. Biological Psychiatry. 2014, 75(12):982-990. PMID: 24143881.

Modo, M., Kolosnjaj, J., Nicholls, F., Ling, W., Wilhelm, C., Debarge, O., Gazeau, F., Clement, O. Considerations for the clinical use of MRI contrast agents for cell tracking in regenerative medicine. Contrast Media and Molecular Imaging. 2013: 8(6); 439-455. PMID: 24375900.

Rattray, I., Smith, E., Crum, W., Walker, T., Gale, R., Bates, G., Modo, M. Correlations of behavioral deficits with brain pathology assessed through longitudinal MRI and histopathology in the R6/1 mouse model of Huntingtons disease. PLOS One. 2013: 8(12): e84726. PMID: 24367693.

Stille, M., Smith, E., Crum, W.R., Modo, M. 3D reconstruction of 2D fluorescence histology images and registration with in vivo MR images: Application in a rodent model of stroke. Journal of Neuroscience Methods. 2013: 219 (1); 27-40. PMID: 23816399.

Crum, W.R., Giampietro, V.P., Smith, E.J., Gorenkova, N., Stroemer, R.P., Modo, M. A comparison of automated anatomical-behavioural mapping methods in a rodent model of stroke. Journal of Neuroscience Methods 2013: 218 (2); 170-183. PMID: 23727124.

dellAcqua, F, Bodi, I., Slater, D., Catani, M., Modo, M. MR diffusion-based histology and micro-tractography reveal mesoscale features of the human cerebellum. Cerebellum, 2013:12(6); 923-931. PMID: 23907655.

Bible, E., DellAcqua, F., Solanky, B., Bladucci, A., Crapo, P., Badylak, S.F., Ahrens, E.T., Modo, M. Non-invasive imaging of transplanted human neural stem cells and ECM scaffold remodelling in the stroke-damaged rat brain by 19F- and diffusion-MRI. Biomaterials. 2012; 33, 2858-2871. PMID: 22244696.

Vernon AC, Crum WR, Johansson SM, Modo M. Evolution of extra-nigral damage predicts behavioural deficits in a rat proteasome inhibitor model of Parkinson's disease. PLoS One. 2011 Feb 25;6(2):e17269. PubMed PMID: 21364887.
Honors and  
Awards
PubMed Publications   See a listing of publications on PubMed, a service of the National Library of medicine.