Recent Publications

CNS and spinal tumors.

Furtado AD, Panigrahy A, Fitz CR.

2016 136:1139-58. (PMID:  27430462) .  Handb.  Clin Neurol

 

Chronic treatment with haloperidol and olanzapine leads to common and divergent shape changes in the rat hippocampus in the absence of grey matter volume loss.

Crum, W.R., Danckaers, F., Huysmans, T., Natesan, S., Modo, M., Sijbers, J., Williams, S.C.R., Kapur, S., Vernon, A.C

2016 Psychological Medicine. 46: 3081-3093. PMID: 27516217.

 

Human neural stem cell-induced endothelial morphogenesis requires paracrine and juxtacrine signaling.

Chou, C-H., Modo, M.

2016 Scientific Reports. 6: 29029. PMID:27374240.

 

ECM hydrogel injection for the treatment of stroke: Characterization of the acute host cell invasion.

Ghuman, H., Massensini, A, Kim, T., Badylak, S.F., Modo, M.

2016 Biomaterials.  91: 166-181. PMID: 27031811.

 

Biomaterial applications in neural therapy and repair.

Ghuman, H., & Modo, M.

2016 Chinese Neurosurgical Journal. 2016;2: 34.

 

Gaining mechanistic insights into cell therapy using magnetic resonance imaging.

Modo, M.

2016 Current Stem Cell Reports. 2016; 2(3); 221-227.

 

Nanoparticles as a technology platform for biomedical imaging. Design and applications of nanoparticles in biomedical imaging.

Bulte, J.W. & Modo, M.

(2016). Springer Verlag.

 

An image-retrieval aided diagnosis system for clustered microcalcifications.

Wang J, Yang Y, Wernick MN, Nishikawa RM.

Biomedical Imaging (ISBI), 2016 IEEE 13th International Symposium on: IEEE, 2016; p. 1076-9.

 

A new bifunctional chelator p-SCN-Bn-NE3TA for Copper-64: synthesis, peptide conjugation, radiolabeling and evaluation for PET imaging.

Gai Y, Sun L, Hui W, Ouyang Q, Anderson CJ, Xiang G, Ma X, Zeng D.

Inorganic Chemistry, 2016; 55:6892-6901.

 

177Lu-Labeled Phosphoramidate-Based PSMA Inhibitors: The Effect of an Albumin Binder on Biodistribution and Therapeutic Efficacy in Prostate Tumor-Bearing Mice.

Choy CJ, Ling X, Geruntho JJ, Beyer SK, Latoche JD, Langton-Webster B, Anderson CJ*, Berkman CE*

Theranostics, in press.

 

Airflow Limitation and Endothelial Dysfunction: Unrelated and Independent Predictors of Atherosclerosis.

Chandra D, Gupta A, Strollo PJ Jr, Fuhrman CR, Leader JK, BonJ, Sivka WA, Shoushtari AH, Avolio J, Kip KE, Reis S, Sciurba FC

Jan 2016 Am J Respir Crit Care Med.

 

Not black or white, but brown: A common finding explained!

Jones M, Rodrigues Y, Patel S, Gozansky E, Soman P

June 2016 J Nucl Cardiol.

 

Erratum to: Not black or white, but brown: A common finding explained!

Jones M, Rodriguez Y, Patel S, Gozansky E, Soman P.

June 2016 J Nucl Cardiol.

 

Correction of motion artifacts and serial correlations for real-time functional near-infrared spectroscopy.

Jeffrey W. Barker, Andrea L. Rosso, Patrick J. Sparto, Theodore J. Huppert

July 2016 Neurophotonics

 

The neural substrates of cognitive flexibility are related to individual differences in preschool irritability: A fNIRS investigation        

Yanwei Li, Adam S. Grabell, Lauren S. Wakschlag, Theodore J. Huppert, Susan B. Perlman                                                                                                                                         

August 2016 Developmental Cognitive Neuroscience

 

Delayed activation of the primary orbitofrontal cortex in post-traumatic anosmia.

Lee VK, Nardone R, Wasco F, Panigrahy A, Zuccoli G.

August 2016  Brain Injury

 

ACR Appropriateness Criteria Fever Without Source or Unknown Origin-Child.

Westra SJ, Karmazyn BK, Alazraki AL, Dempsy ME, Dillman JR, Garber M, Moore SG, Raske ME, Rice HE, Rigsby CK, Safdar N, Simoneaux SF, Strouse PJ, Trout AT, Wootton-Gorges SL, Coley BD

August 2016  Journal of the American College of Radiology

 

False-positive magnetic response imaging findings in follow-up of pediatric patients with tumors of the central nervous system.

De Oliveira SN, Gonzalez-Gomez I, Panigrahy A, Krieger M, McComb G, Finlay JL, Dhall G.

2016 Aug 26;4:2050313X16666232.  (PMID:  27621807)  SAGE Open Med Case Rep.

 

PHACE syndrome is associated with intracranial cavernous malformations.

Foster KA, Ares WJ, Tempel ZJ, McCormick AA, Panigrahy A, Grunwaldt LJ, Greene S.

2016 Aug;32(8):1463: doi: 10.1007/s00381-016-3097-z.  (PMID:  27125518) Childs Nerv Syst.

 

Delayed activation of the primary orbitofrontal cortex in post-traumatic anosmia.

Lee VK, Nardone R, Wasco F, Panigrahy A, Zuccoli G.

2016 Aug 26:1-5: doi:  10.1080/02699052.2016.1199895  (PMID:  27564536)   Brain Inj. 

 

Impact of magnetic resonance imaging on ventricular tachyarrhythmia sensing: Results of the Evera MRI Study

Gold MR, Sommer T, Schwitter J, Kanal E, Bernabei MA, Love CJ, Surber R, Ramza B, Cerkvenik J, Merkely B.

Aug 2016 Heart Rhythm.

 

Immune responses and outcome after vaccination with glioma-associated antigen peptides and poly-ICLC in a pilot for pediatric recurrent low-grade gliomas.

Pollack IF, Jakacki RI, Butterfield LH, Hamilton RL, Panigrahy A, Normolle DP, Connelly AK, Dilbridge S, Mason G, Whiteside TL, Okada H.

2016 Aug;18(8):1157-68.  (PMID:  26984745; PMCID:  PMC4933485)  Neuro-Oncol

 

The correlation between conventional EEG and brain MRI in newborns undergoing hypothermia for hypoxic ischemic encephalopathy.

Obeid R, Sogawa Y, Gedela S, Naik M, Lee V, Talesco R, Wisnowski J, Painter MJ, Panigrahy A.

2016 Aug (in press). Ped Neurol

 

Non-invasive MRI Assessments of Tissue Microstructures and Macromolecules in the Eye upon Biomechanical or Biochemical Modulation.

Ho LC, Sigal IA, Jan NJ, Yang X, van der Merwe Y, Yu Y, Chau Y, Leung CK, Conner IP, Jin T, Wu EX, Kim SG, Wollstein G, Schuman JS, Chan KC.

Aug 2016, 6:32080. doi: 10.1038/srep32080. Scientific Reports

 

Improved spatial accuracy of functional maps in the rat olfactory bulb using supervised machine learning approach.

Murphy MC, Poplawsky AJ, Vazquez AL, Chan KC, Kim SG, Fukuda M.

Aug 15 / 2016, PMID: 27236085 Neuroimage

 

Radium-223 Therapy for Patients with Metastatic Castrate-Resistant Prostate Cancer: An Update on Literature with Case Presentation.

Nguyen NC, Shah M, Appleman LJ, Parikh R, Mountz JM.

Sept 2016   Int J Mol Imaging. 2016

 

MR imaging of a novel NOE-mediated magnetization transfer with water in rat brain at 9.4 T.

Zhang XY, Wang F, Jin T, Xu J, Xie J, Gochberg DF, Gore JC, Zu Z.

Sep 2016. doi: 10.1002/mrm.26396. Magnetic Resonance in Medicine

 

Functional Connectivity of Resting Hemodynamic Signals in Submillimeter Orientation Columns of the Visual Cortex. 

Vasireddi AK, Vazquez AL, Whitney DE, Fukuda M, Kim SG.

Sep 7 / 2016. PMID: 27461173 Brain Connectivity

 

Pulmonary Alveolar Microlithiasis.

Jospeh A. Delic, Carl R. Fuhrman, Humberto E. Trejo Bittar

Sept-Oct 2016 AIRP    Best Cases in Radiologic-Pathologic Correlation

 

Currarino Triad and Multivisceral Anomalies: First Description of a New Association

Giulio Zuccoli, Shobhit Madan, Sameh Tadros, Samuel A. Lindner and Ashok Panigrahy (Children Hospital of Pittsburgh)

10/2016  Neurographics

 

Thickening of the cauda equina roots: a common finding in Krabbe disease,

Hwang M, Zuccoli GZ, Panigrahy A, Poe MD, Escolar Ml. 

2016 Oct;26(10):3377-82. doi: 10.1007/s00330-016-4233-6 (PMID:  27137647) .  Eur Radiol.

 

Discordant Observation of Brain Injury by MRI and Malignant Electroencephalography Patterns in Comatose Survivors of Cardiac Arrest following Therapeutic Hypothermia

J.M. Mettenburg, V. Agarwal, M. Baldwin and J.C. Rittenberger

October 2016, 37 (10) 1787-1793; DOI: https://doi.org/10.3174/ajnr.A4839 American Journal of Neuroradiology

 

Brain dysplasia associated with ciliary dysfunction in congenital heart disease infants.

Panigrahy A, Lee V, Cecshin R,  Zuccoli G, Beluk N, Khalifa O, Votava-Smith JK,  DeBrunner M,  Munoz R, Domina Y, Morell V, Wearden P,  Sanchex De Toledo J, Devine W, Zahid M, Lo CW.

2016 Nov;178:141-148.  (PMID:  27574995) .    J Pediatr

 

Brian Dysplasia Associated with Ciliary Dysfunction in Infants with Congential Heart Disease.

Panigrahy A, Lee V, Ceschin R, Zuccoli G, Beluk N, Khalifa O, Votava-Smith JK, DeBrunner M, Munoz R, Domnina Y, Morell V, Wearden P, Sanchez De Toledo J, Devine W, Zahid M, Lo CW.

November 2106 Journal of Pediatric

 

Do dermatomyositis and polymyositis affect similar thigh muscles? A comparative MRI based study.

Pipitone N, Notarnicola A, Levrini G, Spaggiari L, Scardapane A, Iannone F, Lapadula G, Pattacini P, Zuccoli G, Salvarani C.

November 2016  Clinical Exp Rheumatology

 

The incredible srinking problem of the device patient.

Kanal, E

Nov 2016 Heart Rhythm

 

Pediatric Epilepsy: Neurology, Functional Imaging, and Neurosurgery

Mountz JM, Patterson CM, Tamber MS.

Nov 2016      Semin Nucl Med. 2017 Mar

 

Recommended responsibilities for management of MR safety

Calamante F, Ittermann B, Kanal, E. Inter-Society Working Group on MR Safety

Nov 2016 Magn Reson Imaging

 

Standing balance and strength measurements in older adults living in residential care communities.

Bader A. Alqahtani, Mary Ann Ferchak, Theodore J. Huppert, Ervin Sejdic, Susan L Greenspan, Patrick J. Sparto

December 2016 Aging Clinical and Experimental Research

 

Development venous anomaly presenting as a spontaneous intraparenchymal hematoma without thrombosis.

Agarwal N, Zuccoli G, Murdoch G, Jankowitz BT, Greene S.

December 2016   Neuroradiology

 

Antigen-specific immunoreactivity and clinical outcome following vaccination with glioma-associated antigen peptides in children with recurrent high-grade gliomas:  results of a pilot study.

Pollack IF, Jakacki RI, Butterfield LH, Hamilton RL, Panigrahy A, Normolle DP, Connelly AK, Dilbridge S, Mason G, Whiteside TL, Okada H.

2016 dec;130(3):517-27.  (PMID:  27624914           J Neuroonncol. 

 

Gadolinium Based contrasts agents (GBCA): Safety overview after 3 decades of clinical experience

Kanal, E

Dec 2016 Magn Reson Imaging

 

Glucose metabolism-weighted imaging with chemical exchange-sensitive MRI of 2-deoxyglucose (2DG) in brain: Sensitivity and biological sources.

Jin T, Mehrens H, Wang P, Kim SG.

Dec 2016;143:82-90. Neuroimage

 

Accrual Patterns for Clinical Studies Involving Quantitative Imaging: Results of an NCI Quantitative Imaging Network (QIN) Survey.

Kurland BF, Aggarwal S, Yankeelov TE, Gerstner ER, Mountz JM, Linden HM, Jones EF, Bodeker KL, Buatti JM.

Dec 2016 Tomography

 

Standing balance and strength measurements in older adults living in residential care communities.

Bader A. Alqahtani, Mary Ann Ferchak, Theodore J. Huppert, Ervin Sejdic, Susan L Greenspan, Patrick J. Sparto.

December 2016 Aging Clinical and Experimental Research

 

Nanoparticles for PET imaging of tumors and cancer metastasis.

In: Design and Applications of Nanoparticles in Biomedical Imaging (pp 229-255).

Abadjian MC, Choi J, Anderson CJ. J. Bulte and M Modo (eds).

Springer, New York.  2017.

 

Preclinical evaluation of 18F-ML-10 to determine timing of apoptotic response to chemotherapy in solid tumors. 

Demirci E, Ahmed R, Ocak M, Latoche J, Radelet A, DeBlasio N, Mason NS, Anderson CJ*, Mountz JM*.

Molecular Imaging, 2017; 16:1-8.

 

Unexpected global impact of VTA dopamine neuron activation as measured by opto-fMRI.

Lohani S*, Poplawsky AJ*, Kim S-G, Moghaddam B.

2017 Molecular Psychiatry, 22, 585-594.

* co-first authors

 

Estimating the Accuracy Level Among Individual Detections in Clustered Microcalcifications.

de Cea MS, Nishikawa RM and Yang Y.

2017 IEEE Transactions on Medical Imaging. (in press).

 

Optimal reconstruction and quantitative image features for Computer‐Aided Diagnosis tools for breast CT.

Lee J, Nishikawa RM, Reiser I, Boone JM.

2017 Medical Physics. (in press)

 

Agreement between a computer-assisted tool and radiologists to classify lesions in breast elastography images.

Marcomini KD, Fleury EFC, Oliveira VM, Carneiro AO, Schiabel H, Nishikawa RM

Proc. SPIE 2017:10134, 101342T-101342T8.

 

Neutrosophic segmentation of breast lesions for dedicated breast CT.

Lee J, Nishikawa RM, Reiser IS, Boone JM. 

Proc. SPIE 2017:10134, 101340Q-101340Q7.

 

A comparison of exogenous labels for the histological identification of transplanted neural stem cells.

Nicholls, F.J., Liu, J.R., Modo, M.

2017 Cell Transplantation. 2017; 26: 625-645. PMID: 27938486.

 

Correlations of behavioral deficits with brain pathology assessed through longitudinal MRI and histopathology in the HdhQ150/Q150 mouse model of Huntington’s disease.

Rattray, I., Smith, E., Crum, W., Walker, T., Bates, G., Modo, M.

2017 PLOS1. 2017; 18(2): e0168556. PMID: 28088507.

 

Diamagnetic chemical exchange saturation transfer (dia-CEST) affords magnetic resonance imaging of extracellular matrix hydrogel implantation in a rat model of stroke.

Jin, T., Nicholls, F.J., Ghuman, H., Badylak, S.F., Modo, M.

2017 Biomaterials. 2017; 113:176-190. PMID: 27816001.

 

Multi-GPU Acceleration of Branchless Distance Driven Projection and Backprojection for Clinical Helical CT.

Mitra, Ayan, David G. Politte, Bruce R. Whiting, Jeffrey F. Williamson, and Joseph A. O’Sullivan.

Journal of Imaging Science and Technology 61, no. 1 (2017): 10405-1.

 

Design and applications of nanoparticles in biomedical imaging.

Bulte, J. & Modo, M.

2017. Springer Verlag. 

 

"Multi-GPU Acceleration of Branchless Distance Driven Projection and Backprojection for Clinical Helical CT." 

Mitra, Ayan, David G. Politte, Bruce R. Whiting, Jeffrey F. Williamson, and Joseph A. O’Sullivan

2017 Journal of Imaging Science and Technology 61, no. 1 (2017): 10405-1.

 

Tractography in the clinics: a pipeline to characterize early brain development.

Yepes-Calderon F, Lao Y, Fillard P, Nelson MD, Panigrahy A, Leporé N.

2017; Jan (in press). NeuroImage: Clin.

 

Persistent Breast Pain Among Women With Histories of Breast-conserving Surgery for Breast Cancer Compared with Women without Histories of Breast Surgery or Cancer.           

Edmond SN, Shelby RA, Keefe FJ, Fisher HM, Schmidt JE, Soo MS, Skinner CAS, Ahrendt GM, Manculich J, Sumkin JH, Zuley ML, Bovbjerg DH.

Jan 2017 Clin J Pain; 33(1): 51-56

 

Myositis-associated usual interstitial pneumonia has a better survival than idiopathic pulmonary fibrosis.

Aggarwal R, McBurney C, Schneider F, Yousem SA, Gibson FK, Lindell K, Fuhrman CR, Oddis CV.

Jan 2017 Rheumatology

 

Comparison of group-level, source localized activity for simultaneous functional near-infrared spectroscopy-magnetoencephalography and simultaneous fnirs-fmri during parametric median nerve stimulation.

Theodore Huppert, Jeff Barker, Benjamin Schmidt, Shawn Walls, Avniel Ghuman.

January 2017 Neurophotonics

 

Clinical factors associated with cerebral metabolism in term neonates with congenital heart disease.

Harbison AL, Votava-Smith J, del Castillo S, Kumar SR, Lee V, Schmithorst V, Lai HA, O’Neil S, Blüml S, Paquette A, Panigrahy A.

2017 Jan (in press).  (PMID:  28109537) J Pediatr.

 

Diamagnetic chemical exchange saturation transfer (diaCEST) affords magnetic resonance imaging of extracellular matrix hydrogel implantation in a rat model of stroke. 

Jin T, Nicholls FJ, Crum WR, Ghuman H, Badylak SF, Modo M.

Jan 2017;113:176-190. Biomaterials

 

Multi-site quality and variability analysis of 3D FDG PET segmentations based on phantom and clinical image data.

Beichel RR, Smith BJ, Bauer C, Ulrich EJ, Ahmadvand P, Budzevich MM, Gillies RJ, Goldgof D, Grkovski M, Hamarneh G, Huang Q, Kinahan PE, Laymon CM, Mountz JM, Muzi JP, Muzi M, Nehmeh S, Oborski MJ, Tan Y, Zhao B, Sunderland JJ, Buatti JM.

Feb 2017 Med Phys

 

Validating an image-based fNIRS approach with fMRI and a working memory task Sobanawartiny Wijeakumara.

Theodore J. Huppert, Vincent A. Magnotta, Aaron T. Buss, John P. Spencer.

February 2017 NeuroImage

 

Incidence of neuroepithelial primary brain tumors among adult population of Emilia-Romagna Region, Italy

Baldin E, Testoni S, de Pasqua S, Ferro S, Albani F, Baruzzi A, D'Alessandro R; On behalf of PERNO study group.

February 2017 Neurology Science

 

Neuroimaging of peptide based vaccine therapy in pediatric brain tumors: initial experience.

Furtado AD, Ceschin R, Blüml S, Schnur J, Mason G, Jakacki RI, Okada H, Pollack IF, Panigrahy A.

2017 Feb;27(1):155-166.  (PMID:  27889021; PMCID:  PMC5127439)  A. Neuroimaging Clin N Am.

 

Motor sequence learning-induced neural efficiency in functional brain connectivity.

Helmet T. Karim, Theodore J. Huppert, Kirk I. Erickson, Mariegold E. Wollam, Patrick J. Sparto, Ervin Sejdić, Jessie M. VanSwearingen.

February 2017 Behavioural Brain Research

 

Evidence of Non-Linear Associations between Frustration-Related Prefrontal Cortex Activation and the Normal:Abnormal Spectrum of Irritability in Young Children.

Adam S. Grabell, Yanwei Li, Jeff W. Barker, Lauren S. Wakschlag, Theodore J. Huppert, Susan B. Perlman.

March 2017 Journal of Abnormal Child Psychology

 

CD8-Positive T-Cell Leukoencephalitis With Astrocytopathy Clinically Presenting as Neuromyelitis Optica.

Thomas DL, Manners J, Marker D, Mettenburg J, Murdoch G, Stevens B, Wang G, Wiley C.

J Neuropathol Exp Neurol.

2017 Mar 16. Doi: 10.1093/jnen/nlx015.

 

DCE-MRI Background Parenchymal Enhancement Quantified from an Early versus Delayed Post-contrast Sequence: Association with Breast Cancer Presence, Scientific Reports,

Shandong Wu, Margarita Zuley, Wendie A. Berg, Brenda F Kurland, Rachel Jankowitz, Jules Sumkin, David Gur.

Apr. 2017 (Accepted).

 

Functional near-infrared spectroscopy (fNIRS) brain imaging of multi-sensory integration during computerized dynamic posturography in middle-aged and older adults.

Chia-Cheng Lin, Jeffrey W. Barker. Patrick J. Sparto, Joseph M. Furman, Theodore J. Huppert.

April 2017 Experimental Brian Research

 

DCE-MRI Background Parenchymal Enhancement Quantified from an Early versus Delayed Post-contrast Sequence: Association with Breast Cancer Presence

Shandong Wu, Margarita Zuley, Wendie A. Berg, Brenda F Kurland, Rachel Jankowitz, Jules Sumkin, David Gur.

April 2017 (Accepted) Scientific Reports

 

Apparent Diffusion Coefficient (ADC) of the vitreous humor and Subsceptibility Weighted Imaging (SWI) of the retina in abused children with retinal hemorrhages.

Marchione VD, Zuccoli JR, Abelleyro MM, Radic CP, Neme D, Candela M, de Tezanos Pinto M, De Brasi CD, Rossetti LC.

April 2017  Clinical Imaging