Profile Detail

Nghi Nguyen, MD, PhD

Associate Professor
Director of Pediatric Nuclear Medicine


Interest (in 3 to 10 words):

Medical / Graduate School Eberhard Karls University Tuebingen, Germany (2000)
Residency Nuclear Medicine - Saint Louis University, Missouri (2006)

Nuclear Medicine - Eberhard Karls University Tuebingen, Germany
Clinical / Post-doctoral Fellowship PET/CT Fellowship - Saint Louis University, Missouri

Research Fellowship - Case Western Reserve University
Current Society of Nuclear Medicine and Molecular Imaging (2004 - Present)

Radiological Society of North America(2004 - Present)
& Programs
Nuclear Medicine
Digital Imaging
Clinical Interest Oncologic PET/CT and PET/MRI - diagnosis and treatment response evaluation

Neurological PET/MRI - neurodegenerative disease, pseudoprogression of brain tumors

Radioiodine ablation for benign and malignant thyroid diseases

Lu-177 Lutathera therapy for neuroendocrine tumors
Research Interest Oncological and neurological PET/CT and PET/MRI

Clinical evaluation of digital PET imaging (direct photon counting technology)

Enhanced visualization of fused PET/CT and SPECT/CT images using a multipurpose CT window.

Effect of Gd contrast (dimeglumine gadobenate) on brain MRI signal intensity and FDG metabolism.

Artificial intelligence for real-time monitoring of nuclear medicine data acquisition and analysis.
Selected Publications   Refereed Articles

1. Fenchel M, Helber U, Simonetti OP, Stauder NI, Kramer U, Nguyen CN, CD Claussen, S Miller. Multislice first-pass myocardial perfusion imaging: Comparison of saturation recovery (SR)-TrueFISP-two-dimensional (2D) and SR-TurboFLASH-2D pulse sequences. J Magn Reson Imaging 2004; 19(5): 555-63.

2. Nguyen NC, Chaar C, Osman MM. Prevalence and patterns of soft tissue metastasis: Detection with true whole-body F-18 FDG PET/CT. BMC Medical Imaging 2007, 7:8.

3. Nguyen NC, Sayed MM, Taalab K, Osman MM. Spinal cord metastases from lung cancer: Detection with F-18 FDG PET/CT. Clin Nucl Med 2008; 33:356-358.

4. Hueser CN, Nguyen NC, Osman M, Havlioglu N, Patel AJ. Extrapulmonary small cell carcinoma: involvement of the brain without evidence of extracranial malignancy by serial PET/CT scans. World J Surg Oncol 2008, 6:102.

5. Nguyen NC, Akdumen IE, Sayed MM, Oliver D, Osman MM. Increased F-18 FDG uptake in the posterior ocular bulb is associated with brain metastasis: A retrospective study. AJR 2008; 191:W268W274.

6. Nguyen NC, Tran I, Hueser CN, Oliver D, Farghaly HR, Osman MM. F-18 FDG PET/CT characterization of talc pleurodesis-induced pleural changes over time: A retrospective study. Clin Nucl Med 2009;34: 886890.

7. Farghaly HR, Muzaffar R, Bohle RJ, Nguyen NC, Osman MM. Patterns and prevalence of misregistration in F-18 FDG PET/CT. Egyptian J Nucl Med. 2009; 2(2):55-64.

8. Sayed MH, Farghaly HR, Nguyen NC, Mostafa MS, Mekkawy MA, Osman MM. Extrapulmonary small cell carcinoma in prostate: Detection with 18F-FDG PET/CT. Clin Nucl Med. 2010;35(1):38-9.

9. Moinuddin A, Nguyen NC, Osman MM. Careful evaluation of CT findings of a cardiac viability F-18 FDG PET/CT study leading to detection of esophageal cancer. Clin Nucl Med. 2010;35(5):335-7.

10. Fesler MJ, Nguyen NC, Petruska PJ. Modified escalated BEACOPP as salvage chemotherapy in classic Hodgkin lymphoma. Int J Hematol. 2010;92(1):211-3.

11. Nguyen NC, Hueser CN, Kaushik A, Farghaly HR, Osman MM. F-18 fluorodeoxyglucose positron emission tomography/computed tomography findings of an unusual breast lymphoma case and concurrent cervical cancer: a case report. J Med Case Reports. 2010;4:282.

12. Huston SF, Abdelmalik AG, Nguyen NC, Farghaly HR, Osman MM. Whole-Body 18F FDG-PET/CT: The need for a standardized field of view-A referring-physician aid. J Nucl Med Technol. 2010;38(3):123-7.

13. Osman MM, Chaar BT, Muzaffar R, Oliver D, Reimers HJ, Walz B, Nguyen NC. 18F-FDG PET/CT of patients with cancer: Comparison of whole-body and limited whole-body technique. AJR Am J Roentgenol. 2010;195(6):1397-403.

14. Abdelmalik A, Osman MM, Nguyen NC. Squamous cell carcinoma of the bulbar conjunctiva seen on F-18 FDG PET/CT. Clin Nucl Med. 2010;35(12):962-4.

15. Osman MM, Altinyay ME, Abdelmalik AG, Brickman TM, Varvares MA, Nguyen NC. FDG PET/CT incidental diagnosis of a synchronous bladder cancer as a fourth malignancy in a patient with head and neck cancer. Clin Nucl Med. 2011;36(6):496-7.

16. Nguyen NC, Kaushik A, Wolverson MK, Osman MM. Is there a common SUV threshold in oncological FDG PET/CT, at least for some common indications? A retrospective study. Acta Oncol. 2011;50(5):670-7.

17. Muzaffar R, Kudva G, Nguyen NC, Osman MM. Incidental diagnosis of thrombus within an aneurysm on 18F-FDG PET/CT: Frequency in 926 Patients. J Nucl Med. 2011; 52:14.

18. Aygen M, Amirmokri P, Berk F, Nguyen N, Bastani B, Civelek AC. A preliminary report on (99m)Tc-fanolesomab imaging of renal allograft. Nucl Med Commun. 2011;32(10):925-8.

19. Mansouri AM, Vejdani K, Bastani B, Nguyen NC. Calculation of renal differential function following renal transplant: retrospective validation of a simplified method. Clin Nucl Med. 2012;37(10):931-8.

20. Nguyen NC, Vejdani K, Geller TJ. Cerebral FDG metabolic pattern in pediatric patients with neurofibromatosis type 1: A retrospective study. Br J Med Med Res. 2013;3(4):1659-1670.

21. Allam T, Muzaffar R, Nguyen NC, Osman MM. Peritoneal mouse as detected on (18)F-FDG PET-CT. Front Oncol. 2013;3:83.

22.Hu L, Stehning C, Nguyen N, Andrew Sher, Rios CM, Hu Z, Shao L. MR based PET attenuation correction (MRAC) and anatomical localization of human brain using an optimized UTE mDixon pulse sequence. 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) 2014:1-2. doi: 10.1109/NSSMIC.2014.7431028.

23. Paspulati RM; Partovi S; Herrmann KA; Krishnamurthi S; Conor DP; Nguyen NC. Comparison of hybrid FDG PET/MRI compared with PET/CT in colorectal cancer staging and restaging: A pilot study. Abdom Imaging 2015;40(6):1415-25. doi: 10.1007/s00261-015-0474-0.

24. Nguyen NC; Vercher-Conejero J; Sattar A; ODonnel1 J; Faulhaber P. Image quality and diagnostic performance of a digital PET prototype in patients with oncologic diseases: Initial experience and comparison with analog PET. J Nucl Med. 2015;56(9):1378-85. doi: 10.2967/jnumed.114.148338.

25. Nguyen NC, Abhishek K, Nyon S, Farghaly HR. Osman MM, Reimers H-J. Are there radiographic, metabolic and prognostic differences between cavitary and non-cavitary non-small-cell lung carcinoma? A retrospective FDG PET/CT study. Ann Thorac Med. 2015;10(4). doi: 10.4103/1817-1737.165296.

26.Nguyen NC, Khan M, Shah, M. Primary B-cell lymphoma of the pelvic bone in a young patient: Imaging features of a rare case. Cancer Research Frontiers. 2017; 3(1): 51-55. doi: 10.17980/2017.51.

27.Nguyen NC, Yee MC, Tuchayi AM, Kirkwood JM, Tawbi,H. Mountz JM. Targeted therapy and immunotherapy response assessment with F-18 FLT PET/MRI in melanoma brain metastasis: A pilot study. A pilot study. Front. Oncol. 8:18. doi: 10.3389/fonc.2018.00018.

28.Nguyen NC, Vejdani K. Multipurpose CT window for fusion display with functional imaging. World J Nucl Med 2018;17:145-50. doi: 10.4103/wjnm.WJNM_34_17.

29.Nguyen NC, Osman MM. Normalized subtraction of serial brain magnetic resonance images and fludeoxyglucose-positron emission tomography images for tumor treatment monitoring: Case report and method description. J Clin Imaging Sci 2018;8:25. doi: 10.4103/jcis.JCIS_14_18.

30. Nguyen NC, Vercher-Conejero J, Faulhaber P. Tumor volume delineation: A pilot study comparing a digital positron-emission tomography prototype with an analog positron-emission tomography system. World J Nucl Med 2019;18:45-51. doi: 10.4103/wjnm.WJNM_22_18.

31.Nguyen NC, Muthukrishnan A, Mountz, JM. Differential F-18 FDG and F-18 fluciclovine uptake pattern in a patient with poorly differentiated adenocarcinoma of the lung and prostate cancer biochemical recurrence. Clin Nucl Med. 2020;45(1):e63-e64. DOI: 10.1097/RLU.0000000000002781.

Invited Papers, Letters to the Editors, Magazine Interviews, and Book Chapters

1. Osman M, Wall A, Miller MD, Nguyen N, Oliver D, Bucholz RD, Walz BJ. F-18 FDG PET/CT for treatment planning and follow-up. In: HC Urschel, Jr., JJ Kresl, JD Luketich, L Papiez, RD Timmerman (Eds.): Treating tumors that move with respiration. Springer; 2007, p. 55-61.

2. Nguyen NC, Akduman I, Osman MM. F-18 FDG PET and PET/CT imaging of cancer patients. J Radiol Nurs 2008; 27:61-69.

3. Osman MM, Varvares MA, Nguyen NC. Pictorial essay: Nonmalignant FDG uptake in the head and neck regions. PET Clin 2008, 2(4), 445-468.

4. Nguyen NC, Taalab K, Osman MM. Decreased blood flow with increased metabolic activity: A novel sign of pancreatic tumor aggressiveness. Clin Cancer Res. 2010;16(1):367.

5. Nguyen NC, Bhatla D, Osman MM. 123I-MIBG scintigraphy and 18F-FDG PET in neuroblastoma. J Nucl Med. 2010;51(2):330-1.

6. Nguyen NC, Abdelmalik A, Moinuddin A, Osman MM. Detection of Pulmonary Embolism: Comparison of Methods. JNM 2010;51(5):823-24.

7. Nguyen NC, Fajnwaks P, Osman MM, Farghaly HR. 18F-FDG PET for routine posttreatment surveillance in oral and oropharyngeal squamous cell carcinoma. JNM 2010; 51(7):1164.

8. Magazine interview by Mahdoubi, KF. 18F-FDG PET Breaks New Ground in Small Cell Lung Cancer. Molecular Imaging Insight 2011; 5(4): 10-11.

9. Nguyen NC, Osman MM. F18-FDG-PET/CT standardised uptake value threshold in discriminating benign vs. malignant lesions. Doubts and certainties in the era of evidence-based medicine. Acta Oncol. 2012;51(1):123-124.

10. Nguyen N, Montagnese J, Rogers LR, Wolansky L. Positron emission tomography/magnetic resonance imaging (PET/MRI) in the evaluation of brain tumors: Current status and future prospects. Semin Roentgenol. 2014;49(3): 275-289. doi: 10.1053/

11. Nguyen NC, Shah M, Appleman LJ, Parikh R, Mountz JM. Radium-223 therapy for patients with metastatic castrate-resistant prostate cancer: An update on literature with case presentation. Int J Mol Imaging. 2016; 2568031. doi:10.1155/2016/2568031.
Honors and  
Marquis Who's Who in America, 66th Edition (2012)

First Annual Resident Research Poster Competition - 2nd Place. Saint Louis University School of Medicine (2007)
PubMed Publications   See a listing of publications on PubMed, a service of the National Library of medicine.