Profile Detail

Robert Nishikawa, PhD


Interest (in 3 to 10 words):

Medical / Graduate School University of Toronto, CanadaM.Sc. 1984Medical Biophysics
University of Toronto, CanadaPh.D. 1990Medical Biophysics
Clinical / Post-doctoral Fellowship
& Programs
Digital Imaging
Clinical Interest
Research Interest Evaluation of computer-aided diagnosis systems for breast imaging.
Development of quantitative imaging and radiomic methods for breast imaging.
Improving the efficacy of mammographic screening.
Selected Publications   1.Jiang Y, Metz CE, Nishikawa RM: An ROC partial area index for highly sensitive diagnostic tests. Radiology 201:745-750, 1996. PMID: 8939225
2.Nishikawa RM, Schmidt RA, Linver MN, Edwards AV, Papaioannou J, Stull MA. Clinically missed cancer: how effectively can radiologists use computer-aided detection? American Journal of Roentgenology 2012;198(3):708-716. PMID: 22358014
3.Nishikawa RM, Mawdsley GE, Fenster A, Yaffe MJ. Scanned-projection digital mammography. Medical Physics 1987;14(5):717-727. PMID: 3683300
4.Nishikawa RM, Yaffe MJ, Holmes RB. Effect of finite phosphor thickness on detective quantum efficiency. Medical Physics 1989;16(5):773-780. PMID: 2811759
5.Jiang Y, Nishikawa RM, Wolverton DE, Metz CE, Giger ML, Schmidt RA, Vyborny CJ, Doi K. Malignant and benign clustered microcalcifications: automated feature analysis and classification. Radiology. 1996;198(3):671-678. PMID: 8628853
6.Jiang Y, Nishikawa RM, Schmidt RA, Metz CE, Giger ML, Doi K. Improving breast cancer diagnosis with computer-aided diagnosis. Academic Radiology 1999;6(1):22-33. PMID: 9891149
7.Reiser I, Nishikawa RM, Giger ML, Boone JM, Lindfors KK, Yang K. Automated detection of mass lesions in dedicated breast CT: a preliminary study. Medical Physics 2012;39(2):866-873. PMCID: 3277607
8.Reiser I, Nishikawa RM. Task-based assessment of breast tomosynthesis: effect of acquisition parameters and quantum noise. Medical Physics 2010;37(4):1591-1600. PMCID: 2852443
9.Reiser I, Nishikawa RM, Edwards AV, Kopans DB, Schmidt RA, Papaioannou J, Moore RH. Automated detection of microcalcification clusters for digital breast tomosynthesis using projection data only: a preliminary study. Medical Physics 2008;35(4):1486-1493. PMCID: 2811555
10.Nishikawa RM: Assessment of the performance of computer-aided diagnosis and computer-aided diagnosis systems. Seminars in Breast Disease 2002;5(4):217-222, 2002.
11.Nishikawa RM, and Pesce LL: Computer-aided detection evaluation methods are not created equal. Radiology 2009:251:634-636. PMID: 19474371
12.Nishikawa RM, Pesce LL. Estimating sensitivity and specificity for technology assessment based on observer studies. Academic Radiology 2013;20(7):825-830. PMID 23660073
13.Nishikawa RM: Methods for evaluating the effectiveness of screening mammography are not necessarily valid for evaluating the effectiveness of computer-aided detection in screening mammography. Digital Mammography. Lecture Notes in Computer Science 2012;7361:705-712
14.Gur D, Nishikawa RM, Sumkin JH. New screening technologies and practices: a different approach to estimating performance improvement using data from the transition period. Radiology 2014: 275(1), 9-12. PMIC in process.
15.Engstrm E, Reiser I, and Nishikawa RM: Comparison of power spectra for tomosynthesis projections and reconstructed images. Medical Physics 2009;36: 1753-1758. PMCID: 19544793
Honors and  
Fellow of American Association of Physicists in Medicine, 2003
Fellow of the Society of Breast Imaging, 2013
Distinguished Investigator, Academy of Radiology Research, 2014
Senior Member, SPIE - The International Society for Optics & Photonics, 2015
Fellow of the College of American Institute for Medical and Biological Engineering (AIMBE), 2016
PubMed Publications   See a listing of publications on PubMed, a service of the National Library of medicine.